Monday 8 April 2013

Human folly and the power of Malaria clash in Shah's The Fever

From The Week of April 1, 2013

From trees to tigers, from eagles to kelp, evolution has shaped our world for billions of years. Without it, Earth would be little more than a volcanically active water world with a few single-celled organisms listlessly occupying various oceanic vents and superficial pools. There would be no other life, nothing to revel and no one to do the revelling. It is, then, a necessary driver of permanent change. But for all that humanity would not exist without evolution's many gifts, it also presents some problems. For what worked to create us can just as easily work to create things to kill us. Evolution was not a means to our end. It is a means to the development of life. And for all that we may have outpaced our fellow species on the race to intellect, we have not, and never will, corner the market on the right to exist. This is made chillingly clear in Sonia Shah's sweeping biography of a most pernicious and persistent disease.

For nearly half the lifespan of the human species, Malaria has infected our world. Generated from pools of stagnant water in which mosquito larvae happily grow, this crippling illness spreads from these humid nurseries in the saliva of female mosquitos who, with every successful attack upon a living target, inject Malaria's devastating payload into the bloodstreams of their unwitting victims. From there, the disease spreads to the liver, a base from which it can, over the next few weeks, cause havoc to its host, lashing it with debilitating fevers and headaches which, if sufficiently severe, can be fatal. Even if malaria was self-aware, though, it would not care about these consequences of its existence. For its only purpose is to exist. And this it achieves by infecting the blood of the host, blood which is then slurped up by other mosquitos eager for a meal.

So what can be done about this? Ever since humanity has had the tools to battle disease, it has been fighting Malaria. But though there have been soem successes in creating medicines that armor uninfected hosts against Malaria's impact, there is, as yet, no vaccine. Worse yet, some of the agents developed to fight Malaria have strengthened the disease, bestowing it with teeth it once did not require. Failures in the medicinal front have turned inquisitive minds to the prospect of chemically eradicating Malaria's delivery system, the mosquito, efforts that famously culminated in the widespread application of DDT, a wonder insecticide that soon proved to be a poison chalice. Hopes remain for a vaccine, but until then malaria persists, at the cost of hundreds of thousands of lives a year.

Depicting the pathological, sociological, medical and evolutionary histories of Malaria and its impact on the world, The Fever is a stark account of ingenuity and failure. Ms. Shah weaves a terrifying tapestry of Malaria's causes and effects, a dismaying portrait matched only by her tragic, and at times shocking, account of humanity's calamitous attempts to eliminate this most effective infectious disease. Tales of failed drugs, boastful promises and arrogant assumptions culminate in a truly disturbing portrait of the degree to which humanity leaps before it looks. For so eager are we for cures to the afflictions that trouble our days that we are willing to apply them before we fully understand their consequences, a hastiness that has lead to unimaginable ecological damage.

As much as Ms. Shah's account reserves its most effective blows for these failures, it is equally free with praise for the low-tech methods we've developed to fight Malaria. From mosquito nets to the draining of the stagnant pools that are malaria's breeding ground, the disease has been forced to retreat from many parts of the world. Unfortunately for the impoverished, however, most of these retreats have occurred in the developed world, causing Malaria to be, much like AIDS, a problem experienced by others, elsewhere.

The Fever might well have done with some first-hand accounts of Malaria's impact, the better to exemplify Ms. Shah's arguments. Nonetheless, it is a riveting demonstration of how little we actually control our world and how much we rely upon systems like evolution, that are far older than us, for defenses against the threats that live and grow across Earth's ecology. Wonderfully edifying... (4/5 Stars)

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